Science and Probiotics
Thursday, January 19th, 2012Probiotics – live bacteria (lactobacilli and bifida bacteria) that after ingestion have a positive impact on the reproduction of “useful” organisms, shifting the balance of micro flora in their favour. Probiotics can also be a part of everyday food and usually are contained in probiotic foods such as probiotix drinks.
Prebiotics – are fructose-forming foods that nourish and help to grow probiotic products. Recently, synbiotics were widely used for correction of dysbiosis. These are complex drugs that are composed of both pro- and prebiotics. Synbiotics usually consist of freeze-dried strains of Lactobacillus acidophilus (La-5) and Vifidobacterium animalis (Bb-12), as well as prebiotic ingredient – raftiloza – fructooligosaccharides derived from chicory. The total content of lactic acid bacteria in 1 g of dietary supplements is 1.5 x 109 CFU.
Thus, any synbiotic contains lactic acid bacteria – probiotics, microflora and prebiotics that selectively stimulate the growth and activity required strains of intestinal bacteria. The exclusive formula accelerates the action of synbiotics. Such products prolong the period of living bacteria and help them to colonize the gut which helps to produce more bacteria.
Bifidobacterium
It is now known that the genus Bifidobacterium includes 32 species. They first were isolated and defined by a student Henry Tisser in 1899. In 1905, was his first attempt to use bifidobacterium for therapeutic purposes in patients with diarrhea. Currently, products containing bifidobacterium, referred to as functional foods and consumed on a daily basis.
Most important for gastro-intestinal tract of man are B.bifidum, B.infantis, B.breve, B.longumand B.adolescentis. Currently, new species discovered – B.lactis, B.inopintanum, B.denticolens and others. Bifidobacteria form acetic and lactic acids, but do not form carbon dioxide. The optimum temperature for growth – 37-40 degrees C, pH = 6.5-7.0.Bifidobacteria do not grow in the presence of oxygen for their growth needs bicarbonates, carbohydrates, carbon dioxide. Bifida bacteria are a strictly anaerobic bacteria that make up the bulk of the obligate cavity wall and auto flora large intestine in both children and adults.
Lactobacillus
Lactobacillus acidophilus is a Gram-positive facultative and strictly anaerobic rod-shaped bacterium. Lactobacillus bacteria are found throughout the gastrointestinal tract, are the main as well is in vaginal flora. The source of lactobacillus, colonizing the gastrointestinal tract in infants is mother”s birth canal and breast milk (about 49% of births in the first week have lactobacillus in breast milk). High adhesiveness to mucous membranes and mild antigenic load of lactobacillus contributes to the development of their close association to the mucous membranes, including the formation of surface protective bio layer. Lactobacillus enters into complex relationships with other microorganisms, resulting in suppression of putrefactive and pus-producing bacteria. Antibacterial activity of lactic acid bacteria associated with the formation of antibiotic-similar substances (bacteriocins), the elaboration of the hydrolysis of carbohydrates lactic acid, alcohol, lysozyme. Along with this, many strains of lactobacillus that inhabit the human intestine, can synthesize lactatsins to help them compete with other strains of Lactobacillus lactatsin-responsive.